Patient assistance programs
For over 17 years, the Renassist® team has been helping patients with and without prescription drug coverage identify the Renvela® (sevelamer carbonate) reimbursement solution that is right for them. Call a Renassist case manager for assistance or explore the options below.
No prescription insurance
Renassist Patient Assistance Program (RPAP)
RPAP is designed for patients with financial need who do not have coverage for Renvela® (and/or Hectorol® (doxercalciferol) injection) under any prescription drug benefit, including commercial insurance, Medicare, Medicaid, or other government insurance programs. Learn more.
Standard Medicare Part D
Commercial prescription insurance
Download a list of reimbursement tips to share with your patients.
Could your patient be paying $8.25 or less for Renvela® (sevelamer carbonate)?
- T: 1-800-847-0069
- F: 1-877-363-6732
Email us at:
9:00 am to 4:30 pm EST
Renvela® (sevelamer carbonate) is indicated for the control of serum phosphorus in adults and children 6 years of age and older with chronic kidney disease (CKD) on dialysis.
Renagel® (sevelamer hydrochloride) is indicated for the control of serum phosphorus in patients with chronic kidney disease (CKD) on dialysisImportant Safety Information
- Sevelamer is contraindicated in patients with bowel obstruction and in patients with known hypersensitivity to sevelamer carbonate or sevelamer hydrochloride or to any of the excipients.
- Caution should be exercised in patients with dysphagia, swallowing disorders, and severe gastrointestinal (GI) motility disorders, including severe constipation or major GI tract surgery.
- Common adverse events reported with sevelamer include vomiting, nausea, diarrhea, dyspepsia, abdominal pain, flatulence, and constipation. Other events reported include pruritus, rash, fecal impaction and, less commonly, ileus, bowel obstruction, and bowel perforation.
- Uncommon cases of difficulty swallowing the Renagel or Renvela tablet have been reported. Caution should be exercised in these patients and consideration given to using Renvela suspension in patients with a history of difficulty swallowing.
- Drug-drug interactions may occur with some medications and should be taken into consideration when instructing patients how to take sevelamer.
- Serum bicarbonate and chloride levels should be monitored.
- Follow patients for reduced vitamins D, E, and K (coagulation parameters) and folic acid levels.
- Patients should be informed to take sevelamer with meals and to adhere to their prescribed diets.
Renvela® (sevelamer carbonate) and Renagel® (sevelamer hydrochloride) are used to control phosphorus levels in
- Do not use sevelamer if you have a history of bowel obstruction.
- Talk to your doctor if you have had difficulty swallowing or swallowing disorders; or if you have had digestive tract surgery or other digestive disorders, including severe constipation.
- The most common side effects with sevelamer include vomiting, nausea, diarrhea, upset stomach, abdominal pain, flatulence, and constipation.
- Cases of itching, rash, fecal impaction and, less commonly, slow bowel activity, bowel obstruction, and bowel perforation have been reported.
- Uncommon cases of difficulty swallowing the Renagel or Renvela tablet have been reported. Talk to your doctor if you have difficulty swallowing medicines in tablet form. Renvela powder for oral suspension may be considered by your doctor if you have a history of difficulty swallowing.
- Your doctor should monitor bicarbonate and chloride blood levels.
- Reduced vitamins D, E, and K (clotting factors) and folic acid blood levels may be followed by your doctor.
- Talk to your doctor when taking sevelamer with other medications.
- Promptly contact your doctor if you experience severe abdominal pain, new or worsening constipation, or other severe intestinal symptoms while on sevelamer.
- Take sevelamer with meals and adhere to your prescribed diet.
- Hectorol (doxercalciferol) Injection is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis.
- Hectorol capsules are indicated for the treatment of secondary hyperparathyroidism in patients with Stage 3 or Stage 4 chronic kidney disease not on dialysis and patients with chronic kidney disease on dialysis.
Important Safety Information
- Hectorol is contraindicated in patients with a tendency towards hypercalcemia, or evidence of vitamin D toxicity
- Hectorol injection is contraindicated in patients with previous hypersensitivity to doxercalciferol or any of its ingredients.
- Overdosage of any form of vitamin D is dangerous and may lead to progressive hypercalcemia, which if severe, may require emergency attention.
- Acute hypercalcemia may exacerbate tendencies for cardiac arrhythmias and seizures and may potentiate the action of digitalis drugs.
- Chronic hypercalcemia can lead to generalized vascular and other soft tissue calcification.
- Pharmacologic doses of vitamin D and its derivatives should be withheld during Hectorol treatment to avoid possible additive effects and hypercalcemia.
- The patient should be informed about adherence to instructions about diet, calcium supplementation, and avoidance of the use of nonprescription drugs without prior physician approval. Patients should also be carefully informed about the symptoms of hypercalcemia such as weakness, headache, drowsiness, nausea, vomiting, dry mouth, constipation, muscle pain, bone pain, metallic taste and loss of appetite.
- Uncontrolled serum phosphorus in patients undergoing dialysis may lessen the effectiveness of Hectorol.
- Magnesium-containing antacids and Hectorol should not be administered concomitantly.
- Serious hypersensitivity reactions, including fatal outcome, have been reported post marketing in patients on hemodialysis following administration of Hectorol Injection. Hypersensitivity reactions include anaphylaxis with symptoms of angioedema (involving face, lips, tongue and airways), hypotension, unresponsiveness, chest discomfort, shortness of breath, and cardiopulmonary arrest. These reactions may occur separately or together
- Monitor patients receiving Hectorol Injection upon initiation of treatment for hypersensitivity reactions. Should a hypersensitivity reaction occur, discontinue Hectorol, monitor and treat if indicated
- Patients should be checked and treated for nutritional vitamin D deficiency prior to initiating treatment with Hectorol capsules.
- Cholestyramine may impair intestinal absorption of doxercalciferol capsules.
- Enzyme inducers may affect the 25-hydroxylation of Hectorol and may necessitate dosage adjustments. Cytochrome P450 inhibitors may inhibit the 25-hydroxylation of Hectorol. Formation of the active Hectorol moiety may be hindered.
- Adverse effects of Hectorol injection treatment are: hypercalcemia, hyperphosphatemia, and oversuppression of iPTH. Adverse effects of Hectorol capsules treatment are hypercalcemia, hyperphosphatemia, hypercalciuria, and oversuppression of PTH. These should be managed by regular patient monitoring and appropriate dosage adjustments.
- Serum levels of iPTH, calcium and phosphorus should be determined prior to initiation of Hectorol treatment. During the early phase of treatment they should be determined weekly.
- Adverse events reported by ≥5% of the Hectorol-treated dialysis patients included: edema, headache, malaise, nausea/vomiting, dizziness, dyspnea, pruritus and bradycardia.
- Adverse events occurring at a frequency of ≥5% in patients taking Hectorol capsules with Stage 3 or Stage 4 chronic kidney disease not on dialysis were infection, chest pain, constipation, dyspepsia, anemia, dehydration, depression, hypertonia, insomnia, paresthesia, increased cough, dyspnea and rhinitis.
- This drug should be used during pregnancy only if clearly needed.
- Nursing mothers should discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
- This drug should be used with caution in patients with impaired hepatic function.